Summary
I-131 treatment of Basedow's disease is effective and safe. Relatively high energy
doses to the thyroid in the range of 150—200 Gray are needed in endemic goiter areas,
where immunogenic hyperthyroidism may coincide with functional autonomy. Induction
of euthyroidism by low doses of antithyroid drugs (methimazole, carbimazole) before
I-131 treatment prevents complications and has no significant influence on outcome
of I-131 therapy. As compared to alternative therapeutic modalities, the risks of
I-131 are low.
